What's your favorite NPC of all time?

[Tanzama -CCV-]

Some examples are Nurse Joy, Tingle, Toadsworth, those village bystanders from Fire Emblem that give you tips...

My favorite is Tony and the Fuzzy Pickles Man from Earthbound (they're hilarious!). And yours?  

[Nomega]

The happy mask salesman.  

[Super Cheesio]

Pancho the Cow from Little King's story. Moo.  

[CYBERPUNK PANDA]

The king and the 4th princess you rescue from castle crashers xD
 

[Donovan001]

I would have to say Sakon from Majoras Mask mostly due to the fact that he is the only person on the game you get to blow up  

[Randolf Von Killington]

Hmm....

I'd have to say Bowser-Super Mario Bros.
I love the classics.  

[Paper Sonic]

O'Chunks
Edit: And now a more compiled list:
GLaDOS
Count Bleck
F.L.U.D.D.
Professor E. Gadd
Professor Layton
Luke
Godot
Edgeworth
Francesca Von Karma
Detective Gumshoe
All Pinatas
Moe a.k.a. Kyorosuke
Carrie
All Cragnons
Globox
Baby Globox
Teensies
Sparx
Hunter
Moneybags
Tom Nook
K.K. Slider
Celeste
Blathers
Brewster
Gorons
Zelda
Tetra
Koroks
Skull Kid
Tingle

...I'll stop now XD  

[Le Chapeau]

Nomega

The happy mask salesman.

I'm a fan of Gonzo as well.  

[Xilo The Odd]

best npc ever.  

[Tanzama -CCV-]

~Xiloscent~

best npc ever.

LOL nice  

[Xilo The Odd]

ShisoVienna90

~Xiloscent~

best npc ever.

LOL nice

best part is he plays a semi important role later in the game.  

[L a s t B a s t a r d]

~Xiloscent~

best npc ever.

Oh yeah, I remember that b*****d.  

[GuruGuru214]

I'd hope I don't have to say it.

Besides him, I suppose I'd say Ada Wong (though technically she's a player character now, she used to be an NPC). And also too many to name from the Monkey Island series, like Wally, the Lost Welshman, the Men of Low Moral Fiber, Murray, and so many others... Screw it, that whole series is my favorite NPC.  

[RoseSpirit]

Sheik and Shad from LoZ, GLaDOS from Portal... and Maya Fey. The D/P/Pt rival is adorable, too. XD  

[GuruGuru214]

RoseSpirit

Sheik and Shad from LoZ, GLaDOS from Portal... and Maya Fey. The D/P/Pt rival is adorable, too. XD

...how the hell did I forget GLaDOS?

Also, I love Knuckles as an NPC in Sonic's game in Sonic 3 & Knuckles. They did an excellent job of integrating a decent story without getting in the way of the classic Sonic gameplay (unlike most of their later attempts...), and the point in Hidden Palace Zone where Knuckles finally realizes that Robotnik's been playing him all along is one of my favorite video game moments ever.